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Best NFL Betting Sites 2025 - Top Picks for American Football

When it comes to USA sports betting sites, all are not created equal and it isn't always as easy as it seems. And when it comes to betting on the NFL, it can be even trickier.

Steve Lapinski
Steve Lapinski
Casino Editor

Last updated: 2025-12-08

Chad Nagel
Sports & Betting Editor

SportsBoom offers honest and impartial bookmaker reviews to help you make informed choices. While we may earn commissions through affiliate links, our content remains independent and free from promotional influence. For more information, see our Content Transparency and How We Review pages.

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What to Consider When Choosing an NFL Betting Site?

As the NFL season approaches, many fans look to make the games even more exciting by betting on their favorite teams. However, with so many sportsbooks available to bet on the NFL, it's not easy to know which one is the right fit for you.

Here are some of the key factors worth considering when choosing a place to bet on the NFL:

Odds and Markets

One of the most important aspects of any sports betting site is the odds and markets that they offer to players. Look for sportsbooks that offer competitive odds across the wide range of bet types, including moneylines, point spreads, totals, player props, futures and more.

The more options offered, the more opportunities you will have to spot value.

Bonuses and Promotions

Quality sportsbooks often give potential players enticing bonus and promotion offers, plus they also have lucrative offers to keep existing players with their sportsbook. Bonus types include welcome bonuses, reload bonuses, free bets, and even VIP rewards programs. Just make sure you always read the terms and conditions before you accept a promotion, as there are often wagering requirements and other limitations.

Live Streaming and In-Game Betting

As the games progress (in NFL and other sports), the odds change. One of the most exciting features in today's age of sports betting is in-game betting, giving you the opportunity to make a bet starting in the middle of the game. Odds are adjusted based on the new likeliest outcomes, based on what has previously happened in the game.

Mobile Compatibility


Nowadays, a good mobile web site experience is essential for sports bettors. Look for sites with well-designed and mobile optimized web sites and apps. Test to make sure that apps work when mobile coverage isn't at its best. You don't want to miss an opportunity to place that bet near kickoff.

Social Media Presence and Customer Support

A good indicator of a sportsbook's reputation and customer service is their social media presence. Additionally, look for sportsbooks that have multiple avenues for contact, including live agent chat, e-mail, phone support, and/or a ticket system.

Security and Reputation

When it comes to online sports betting, you should have a site's security at the top of your mind. Read about a site's reputation on review sites before you put your money at risk with them. Also, make sure you choose sites with industry-standard encryption to protect your personal and financial data.

NFL Betting Explained: Types of NFL Bets

With the rise of sports betting apps, NFL fans now have a wide array of betting options available to them. From traditional wagers to more exotic bets, these apps provide a seamless experience for placing your picks.

Let’s explore some of the most popular types of NFL bets available:

Point Spread

The point spread is one of the most common bets in the NFL. In this wager, the favored team must win by a certain number of points (the spread) for a bet on them to be successful. Conversely, the underdog can lose by less than the spread or win outright for the bet to pay out. For example the Chiefs to win by 7 over the Bills, means the Chiefs are favored by 7 points. 

Moneyline

The money line is a straightforward bet on which team will win the game outright, regardless of the point spread. Favorites will have negative odds (e.g., -150), meaning you'd need to risk $150 to win $100. Underdogs will have positive odds (e.g., +130), where a $100 wager would net you $130 in profit if successful. If you can start putting some moneyline bets together in a parlay, then you can rake in some big time cash.

Totals (Over/Under)

In a total bet, you're wagering on whether the combined score of both teams will go over or under a predetermined number set by the sportsbook. These bets are not tied to who wins the game, only the total points scored. So if the total of the Chiefs vs Bills game is 48, if the combined points of both teams are greater than 48, it’s an Over. If the total is less than 48, it’s an Under. If they hit 48 dead-on, that’s a push, and is much harder to predict. 

Props

Prop bets, or proposition bets, allow you to wager on specific player or team milestones within a game, such as how many passing yards a quarterback will have, whether a player will score a touchdown, or the outcome of the coin toss. For example, you could bet that Patrick Mahomes might have +20 rushing yards, and +230 passing yards. Putting multiple player props together can give you a massive payout if you know what you’re doing.

Futures

Futures bets involve wagering on long-term outcomes, such as which team will win the Super Bowl, which player will win MVP, or over/under season win totals for each team. During an offseason, futures are fun to take a bet on as a pre-season prediction. With the 49ers being 5/1 favorites to win the Super Bowl in 2025, a bettor could lock in a good value bet before the season changes the odds.

Parlays

Parlay bets combine multiple wagers into a single bet, offering the potential for a larger payout but requiring every leg of the parlay to be correct. These bets can include any combination of the above bet types. Parlays are where you can big money, or lose it to the greedy casinos and bookmakers. Smart players are able to spot the top contender bets for big games, and put them together in small, but big payout bets. 

With so many betting options available through apps, NFL fans can truly customise their experience and add an extra layer of excitement to every game.

FAQs

Is sports betting legal for the NFL?

Sports betting is currently legal in over 30 U.S. states allow legal NFL wagering. However, laws vary by state, so it's important to check your local regulations.

What's the difference between a point spread and moneyline bet?

A point spread bet factors in a handicap, while a moneyline is simply picking the outright winner. Point spreads aim to make betting lines more balanced.

How do I place a parlay bet?

A parlay combines multiple bets into one wager. All legs of the parlay must hit for it to pay out. The more bets included, the higher the potential payout.

Can I bet on the Super Bowl online?

Yes, all major online sportsbooks offer extensive Super Bowl betting markets each year, including live in-game wagering options. 

What are prop bets?

Prop bets allow you to wager on specific occurrences within a game, like how many passing yards a QB will have or whether a player will score a TD.

How do futures bets work?

Futures are bets on long-term outcomes, such as which team wins the Super Bowl or season win totals. You can bet these wagers well before the season starts.

Betting Tips and Predictions for Betting

Hawaii vs Wyoming – NCAA Football

Hawaii is favored to win this matchup, with a predicted score of 30-17. The Rainbow Warriors have a strong passing offense, while Wyoming's defense is solid but may struggle to keep up. Betting on Hawaii to cover the -8 point spread is recommended, as well as backing the over on the 44.5 total points line for a higher-scoring game.

FOX Sports
Green Bay Packers vs Detroit Lions – NFL

The Packers are favored to edge out the Lions in a high-scoring contest, with a predicted score of 23-17. Both teams have shown offensive efficiency, making the over on the total points line a strong bet. Backing Green Bay to win outright and the game to go over the total is advised for this Thanksgiving matchup.

ESPN
Green Bay Packers vs Detroit Lions – NFL

The Packers are expected to win a close game against the Lions, with a predicted score of 23-17. Both teams have high-paced offenses, so the over on the total points line is a recommended bet. Backing Green Bay to win and the game to exceed the total points is the best strategy for this matchup.

Squawka

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